Wednesday, November 1, 2023

What questions are asked at a QC department interview?

Quality Contol Jobs
Assura Pharma Training Institute


A combination of behavioral and technical questions will be asked during a Quality Control (QC) department interview in the pharmaceutical business in order to evaluate your suitability for the position and your qualifications.

In a quality control interview, you could be asked the following typical questions:

Technical/Profession-Related Questions:

1) How do the tenets of Good Manufacturing Practices (GMP) apply to your position in quality control?

2) Which equipment and testing techniques have you used in a quality control laboratory before?

3) Tell us about your experience using FTIR, UV-Vis, HPLC, GC, and other analytical tools that are frequently used in quality control.

4) How do you go about maintaining and calibrating lab instruments and equipment?

5) In the pharmaceutical sector, what does a stability study mean, and what role have you played in conducting one?

6) What is involved in doing a microbiological limit test and how is it done?

7) Could you explain the processes involved in a normal drug dissolving test?

8) What part does a quality control analyst play in making sure pharmaceutical items are sterile?

9) Describe how you handle and record findings that are not in line with specifications (OOS)?

10) In your QC job, how do you guarantee data integrity and adherence to legal requirements?

Habitual Inquiries:

1) Give an example of a difficult circumstance you faced and how you handled it in a previous QC position.

 2) In a fast-paced quality control setting, how do you prioritize and manage many testing assignments and deadlines?

3) Could you provide an instance when you found a mistake or inconsistency in the QC results? What approach did you take?

4) How do you inform other departments, like Quality Assurance or Production, about QC findings and results?

5) Talk about your experience in a QC context working in a cross-functional team or group.

6) Describe a situation when you had to adjust to modifications in the instruments, processes, or testing techniques. What was your approach?

7) Describe the methods you use to keep the laboratory area neat and orderly so that contamination cannot occur.

8) How do you remain current with changes in legislation that affect your QC function and trends in the industry?

9) Could you give an instance of how, in a prior position, you contributed to the efficiency or quality control process improvements?

10) What appeals to you most about working in quality control, and why would you like to pursue a career in the pharmaceutical industry?

Conclusion

Be ready to give precise instances from your prior employment or educational background to demonstrate your credentials and aptitude for addressing problems. Customize your answers to highlight your pertinent experience, meticulous nature, and dedication to excellence—qualities that the QC department greatly values.


Register

For more information:

Visit our website: https://www.assura.net.in/core-website/admin/register/

Join us on Facebook: https://www.facebook.com/AssuraPharmaTraining

Join us on Instagram: https://www.instagram.com/assurafoundation/

Join us on Youtube: https://www.youtube.com/channel/UC4F5b_iAkwQ1ZrN3GjMLY5A

To Buy Notes: https://www.assura.net.in/buy-notes/ 

Call or Whatsapp on 9175914123 / 7972910842

What are the sophisticated instruments used in pharmaceutical QC?


HPLC
Assura Pharma Training Institute


To guarantee that goods fulfill strict quality and safety requirements, the pharmaceutical sector uses a range of advanced devices for Quality Control (QC). Pharmaceutical raw materials, intermediates, and final products are subjected to physical, chemical, and microbiological analyses and evaluations using these tools.

The following are a few of the advanced tools frequently utilized in pharmaceutical

Quality Control:

High-Performance Liquid Chromatography (HPLC): The potent analytical method known as High-Performance Liquid Chromatography (HPLC) is used to separate, identify, and quantify the various chemicals present in a pharmaceutical sample. It is often employed in the examination of active pharmaceutical ingredients (APIs), impurity profiling, and drug assay.

Gas chromatography (GC): It is a technique for separating and examining volatile substances. It is widely employed in the testing of volatile organic compounds in pharmaceutical goods as well as the examination of residual solvents.

Liquid Chromatography-Mass Spectrometry (LC-MS): This technique uses mass spectrometry and liquid chromatography to identify and quantify medicinal substances, such as tiny molecules, proteins, and peptides.

Fourier Transform Infrared Spectroscopy (FTIR): By analyzing their infrared absorption spectra, chemical substances may be identified using Fourier Transform Infrared Spectroscopy (FTIR). It is useful for figuring out medicinal products' structural and chemical makeup.

Ultraviolet-Visible Spectrophotometry (UV-Vis): UV-Vis spectrophotometers are used to quantify the concentration of analytes in pharmaceutical samples by measuring the absorption of light at particular wavelengths.

Nuclear Magnetic Resonance Spectroscopy (NMR): NMR is useful for structural characterization and validation of medicinal substances since it may be used to clarify the structure of organic molecules.

Dissolution Test Apparatus: To guarantee a steady and regulated release of medication ingredients, the dissolution testing apparatus measures the amount of drug material released from pharmaceutical dosage forms (tablets, capsules, etc.).

 Karl Fischer Titrator: Because moisture content may have a big influence on a product's stability, this tool is used to find out how much water is in pharmaceutical items.

Particle Size Analyzers: Particle size and distribution analysis is a crucial step in guaranteeing consistency and effectiveness in pharmaceutical powders, suspensions, and aerosols.

Atomic Absorption Spectroscopy (AAS): AAS is used to measure the concentration of trace elements in pharmaceutical goods, such as heavy metals, guaranteeing compliance with regulatory limits.

Microbial Identification Systems: For the quick and precise identification of microorganisms in pharmaceutical goods and environmental monitoring, automated systems like MALDI-TOF mass spectrometers are utilized.

Equipment for Sterility Testing: This category comprises incubators, sophisticated filtration systems, and testing techniques used to ascertain if pharmaceutical items are sterile.

Real-Time Polymerase Chain Reaction (PCR): In the context of biotechnology and gene treatments, PCR is particularly useful for identifying and measuring nucleic acids in medications.

High-Throughput Screening (HTS) Systems: These automated systems are useful in early-stage research and drug discovery since they can examine several samples in a high-throughput manner.

Infrared (IR) and Raman Microscopes: These microscopes use a combination of spectroscopy and imaging to examine medicinal materials' chemical makeup and distribution at the microscopic level.

Conclusion

The particular testing specifications, the makeup of the pharmaceutical product, and the industry-governing regulations all play a role in the pharmaceutical quality control instrument selection process. These tools are essential for preserving the safety, quality, and compliance of products with strict restrictions.


Register

For more information:

Visit our website: https://www.assura.net.in/core-website/admin/register/

Join us on Facebook: https://www.facebook.com/AssuraPharmaTraining

Join us on Instagram: https://www.instagram.com/assurafoundation/

Join us on Youtube: https://www.youtube.com/channel/UC4F5b_iAkwQ1ZrN3GjMLY5A

To Buy Notes: https://www.assura.net.in/buy-notes/ 

Call or Whatsapp on 9175914123 / 7972910842

What are the Jobs in microbiology in the pharmaceutical sector?


Microbiology in Pharma
Assura Pharma Training Institute



In the pharmaceutical sector, microbiology is essential for guaranteeing the quality and safety of pharmaceutical goods. In the pharmaceutical industry, microbiologists may work with a variety of microbes, test for contamination, and ensure product sterility. 

The following are a few typical microbiological jobs in the pharmaceutical sector:

Microbiologist: Microbiologists work in the pharmaceutical sector and are in charge of researching and examining microorganisms that might have an impact on the safety and quality of products, such as bacteria, viruses, and fungi. To guarantee product sterility and find any microbiological contamination, they carry out a number of tests.

Quality Assurance Microbiologist: Ensuring quality Microbiologists labor to uphold the strict requirements for product quality. To guarantee adherence to legal criteria, they conduct microbiological testing on pharmaceutical items that are completed, in-process samples, and raw materials.

Environmental Monitoring Specialist: These professionals are in charge of keeping an eye on the sterility and cleanliness of the manufacturing environment for pharmaceuticals. In order to identify possible sources of pollution and carry out necessary remedial action, they gather samples from the air, water, and surface.

Pharmaceutical Research Scientist: Pharmacological microbiological research scientists carry out investigations to create and enhance pharmaceutical goods, such as vaccines, antibiotics, and sterile preparations. They create plans to counteract microbial risks and look into the efficacy of antimicrobial treatments.

Regulatory Affairs Specialist: Microbiology-trained regulatory affairs specialists ensure that pharmaceutical goods adhere to laws governing microbiological contamination, sterility, and quality. They converse with regulatory officials and produce documents for regulatory filings.

Clinical Microbiologist: In the pharmaceutical sector, clinical microbiologists conduct research and clinical trials to evaluate the efficacy and safety of novel pharmaceutical products. They could keep an eye on treatment results and check patient samples for microbiological illnesses.

 Validation Specialist: To guarantee accurate and dependable findings, microbiological testing apparatus and procedures are validated by validation professionals. They are in charge of creating and keeping documentation and validation protocols.

Microbiological Testing Technician: In the lab, these professionals do regular microbiological testing and observation. They could carry out tests for endotoxins, microbial identification, sterility, and microbial limit.

Bioprocess Engineer: Bioprocess engineers work in the biotechnology and biopharmaceutical industries. Their goal is to guarantee the intended product output and quality by refining microbial fermentation methods.

Pharmaceutical Consultant: Skilled microbiologists may advise pharmaceutical businesses on best practices for regulatory compliance, contamination avoidance, and microbial control in their capacity as consultants.

GMP Auditor: Having studied microbiology, Good Manufacturing Practices (GMP) auditors examine pharmaceutical facilities to make sure that GMP regulations are being followed, especially when it comes to microbiological control.

Conclusion

A solid background in microbiology, frequently accompanied by an advanced degree, and a thorough comprehension of regulatory standards, such as Good Manufacturing Practices (GMP) and Good Laboratory Practices (GLP), are generally prerequisites for pursuing a career in microbiology in the pharmaceutical business. The aforementioned jobs play a crucial part in upholding product quality, safety, and compliance within the pharmaceutical industry.


Register

For more information:

Visit our website: https://www.assura.net.in/core-website/admin/register/

Join us on Facebook: https://www.facebook.com/AssuraPharmaTraining

Join us on Instagram: https://www.instagram.com/assurafoundation/

Join us on Youtube: https://www.youtube.com/channel/UC4F5b_iAkwQ1ZrN3GjMLY5A

To Buy Notes: https://www.assura.net.in/buy-notes/ 

Call or Whatsapp on 9175914123 / 7972910842